Localized delivery of immunosuppressive regulatory T cells to peripheral nerve allografts promotes regeneration of branched segmental defects

Segmental injuries to peripheral nerves (PNs) too often result in lifelong disability or pain syndromes due to a lack of restorative treatment options. For injuries beyond a critical size, a bridging device must be inserted to direct regeneration. PN allografts from immunologically incompatible dono...

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Bibliographic Details
Published in:Biomaterials
Main Authors: Roballo, Kelly C. Santos, Dhungana, Subash, Jiang, Zhongliang, Oakey, John, Bushman, Jared S.
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8158786/
https://ncbi.nlm.nih.gov/pubmed/31022556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2019.04.015
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