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Metabolic adaptation in hypoxia and cancer

The ability of tumor cells to adapt to changes in oxygen tension is essential for tumor development. Low oxygen concentration influences cellular metabolism and, thus, affects proliferation, migration, and invasion. A focal point of the cell’s adaptation to hypoxia is the transcription factor HIF1α...

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Bibliographic Details
Published in:Cancer Lett
Main Authors: Paredes, Felipe, Williams, Holly C., Martin, Alejandra San
Format: Artigo
Language:Inglês
Published: 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8158653/
https://ncbi.nlm.nih.gov/pubmed/33444690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2020.12.020
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