Bio-Distribution and Pharmacokinetics of Topically Administered γ-Cyclodextrin Based Eye Drops in Rabbits

The purpose of this study was to evaluate the ocular pharmacokinetics, bio-distribution and local tolerability of γ-cyclodextrin (γCD) based irbesartan 1.5% eye drops and candesartan 0.15% eye drops after single and multiple topical administration in rabbit eyes. In this randomized, controlled study...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Kallab, Martin, Schuetzenberger, Kornelia, Hommer, Nikolaus, Schäfer, Bhavapriya Jasmin, Schmidl, Doreen, Bergmeister, Helga, Zeitlinger, Markus, Tan, Aimin, Jansook, Phatsawee, Loftsson, Thorsteinn, Stefansson, Einar, Garhöfer, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8158513/
https://ncbi.nlm.nih.gov/pubmed/34070168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14050480
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