The Role of ZEB2 in Human CD8 T Lymphocytes: Clinical and Cellular Immune Profiling in Mowat–Wilson Syndrome

The Zeb2 gene encodes a transcription factor (ZEB2) that acts as an important immune mediator in mice, where it is expressed in early-activated effector CD8 T cells, and limits effector differentiation. Zeb2 homozygous knockout mice have deficits in CD8 T cells and NK cells. Mowat–Wilson syndrome (M...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Frith, Katie, Munier, C. Mee Ling, Hastings, Lucy, Mowat, David, Wilson, Meredith, Seddiki, Nabila, Macintosh, Rebecca, Kelleher, Anthony D., Gray, Paul, Zaunders, John James
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8158478/
https://ncbi.nlm.nih.gov/pubmed/34070208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22105324
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