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Loperamide Toxicity Revealing Apical Hypertrophic Cardiomyopathy
Loperamide, a μ-opioid receptor agonist, can cause cardiotoxicity by inhibiting the potassium ion channel and slowing cardiomyocyte repolarization. This, in turn, can lead to frequent early afterdepolarizations, the most common mechanism of drug-induced long QT syndrome and torsades de pointes. Apic...
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| Pubblicato in: | Methodist Debakey Cardiovasc J |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Methodist DeBakey Heart & Vascular Center
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8158447/ https://ncbi.nlm.nih.gov/pubmed/34104323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14797/VRZW9460 |
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