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Conversion from cilostazol to OPC‐13015 linked to mitigation of cognitive impairment

INTRODUCTION: Cilostazol may be a novel therapeutic agent for Alzheimer's disease. Its metabolite, OPC‐13015, has a stronger inhibitory effect on type 3 phosphodiesterase than cilostazol. METHODS: We prospectively enrolled patients with mild cognitive impairment to whom cilostazol was newly pre...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement (N Y)
Main Authors: Saito, Satoshi, Shinmyozu, Kaori, Kawakami, Daisuke, Yamauchi, Miho, Ikeda, Shuhei, Hattori, Yorito, Yamamoto, Rintaro, Hayakawa, Naoki, Ihara, Masafumi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8158162/
https://ncbi.nlm.nih.gov/pubmed/34095441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/trc2.12182
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