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Discovering unknown human and mouse transcription factor binding sites and their characteristics from ChIP-seq data

Transcription factor binding sites (TFBSs) are essential for gene regulation, but the number of known TFBSs remains limited. We aimed to discover and characterize unknown TFBSs by developing a computational pipeline for analyzing ChIP-seq (chromatin immunoprecipitation followed by sequencing) data....

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yu, Chun-Ping, Kuo, Chen-Hao, Nelson, Chase W., Chen, Chi-An, Soh, Zhi Thong, Lin, Jinn-Jy, Hsiao, Ru-Xiu, Chang, Chih-Yao, Li, Wen-Hsiung
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8158016/
https://ncbi.nlm.nih.gov/pubmed/33975951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2026754118
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