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Polymeric Micelles for the Enhanced Deposition of Hydrophobic Drugs into Ocular Tissues, without Plasma Exposure

Commercial topical ocular formulations for hydrophobic actives rely on the use of suspensions or oil in water emulsions and neither of these formulation modalities adequately promote drug penetration into ocular tissues. Using the ocular relevant hydrophobic drug, cyclosporine A (CsA), a non-irritan...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Uchegbu, Ijeoma F., Breznikar, Jan, Zaffalon, Alessandra, Odunze, Uche, Schätzlein, Andreas G.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8157576/
https://ncbi.nlm.nih.gov/pubmed/34069936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13050744
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