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MicroRNA-449a delays lung cancer development through inhibiting KDM3A/HIF-1α axis

BACKGROUND: It has been established that microRNA (miR)-449a is anti-tumorigenic in cancers, including lung cancer. Therefore, this study further explored miR-449a-mediated mechanism in lung cancer, mainly focusing on lysine demethylase 3A/hypoxia-induced factor-1α (KDM3A/HIF-1α) axis. METHODS: miR-...

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Publicat a:J Transl Med
Autors principals: Hu, Shan, Cao, Peng, Kong, Kangle, Han, Peng, Deng, Yu, Li, Fan, Zhao, Bo
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8157436/
https://ncbi.nlm.nih.gov/pubmed/34044859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-021-02881-8
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