Sildenafil Alleviates Murine Experimental Autoimmune Encephalomyelitis by Triggering Autophagy in the Spinal Cord

Multiple Sclerosis (MS) is a neuroinflammatory and chronic Central Nervous System (CNS) disease that affects millions of people worldwide. The search for more promising drugs for the treatment of MS has led to studies on Sildenafil, a phosphodiesterase type 5 Inhibitor (PDE5I) that has been shown to...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Duarte-Silva, Eduardo, Meiry da Rocha Araújo, Shyrlene, Oliveira, Wilma Helena, Lós, Deniele Bezerra, Bonfanti, Amanda Pires, Peron, Gabriela, de Lima Thomaz, Livia, Verinaud, Liana, Peixoto, Christina Alves
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8156813/
https://ncbi.nlm.nih.gov/pubmed/34054847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.671511
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