Sildenafil Alleviates Murine Experimental Autoimmune Encephalomyelitis by Triggering Autophagy in the Spinal Cord

Multiple Sclerosis (MS) is a neuroinflammatory and chronic Central Nervous System (CNS) disease that affects millions of people worldwide. The search for more promising drugs for the treatment of MS has led to studies on Sildenafil, a phosphodiesterase type 5 Inhibitor (PDE5I) that has been shown to...

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Опубликовано в: :Front Immunol
Главные авторы: Duarte-Silva, Eduardo, Meiry da Rocha Araújo, Shyrlene, Oliveira, Wilma Helena, Lós, Deniele Bezerra, Bonfanti, Amanda Pires, Peron, Gabriela, de Lima Thomaz, Livia, Verinaud, Liana, Peixoto, Christina Alves
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8156813/
https://ncbi.nlm.nih.gov/pubmed/34054847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.671511
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