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Stability across the Whole Nuclear Genome in the Presence and Absence of DNA Mismatch Repair

We describe the contribution of DNA mismatch repair (MMR) to the stability of the eukaryotic nuclear genome as determined by whole-genome sequencing. To date, wild-type nuclear genome mutation rates are known for over 40 eukaryotic species, while measurements in mismatch repair-defective organisms a...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Lujan, Scott Alexander, Kunkel, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8156620/
https://ncbi.nlm.nih.gov/pubmed/34067668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10051224
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