Molecular Structure of Cefuroxime Axetil Complexes with α-, β-, γ-, and 2-Hydroxypropyl-β-Cyclodextrins: Molecular Simulations and Raman Spectroscopic and Imaging Studies

The formation of cefuroxime axetil+cyclodextrin (CA+CD) complexes increases the aqueous solubility of CA, improves its physico-chemical properties, and facilitates a biomembrane-mediated drug delivery process. In CD-based tablet formulations, it is crucial to investigate the molecular details of com...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Gieroba, Barbara, Kalisz, Grzegorz, Sroka-Bartnicka, Anna, Płazińska, Anita, Płaziński, Wojciech, Starek, Małgorzata, Dąbrowska, Monika
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8156438/
https://ncbi.nlm.nih.gov/pubmed/34063471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22105238
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