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From Antisense RNA to RNA Modification: Therapeutic Potential of RNA-Based Technologies

Therapeutic oligonucleotides interact with a target RNA via Watson-Crick complementarity, affecting RNA-processing reactions such as mRNA degradation, pre-mRNA splicing, or mRNA translation. Since they were proposed decades ago, several have been approved for clinical use to correct genetic mutation...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Adachi, Hironori, Hengesbach, Martin, Yu, Yi-Tao, Morais, Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8156014/
https://ncbi.nlm.nih.gov/pubmed/34068948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9050550
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