Guhong Injection Protects Against Apoptosis in Cerebral Ischemia by Maintaining Cerebral Microvasculature and Mitochondrial Integrity Through the PI3K/AKT Pathway

Guhong injection (GHI) can be used for the treatment of ischemic stroke. We investigated the antiapoptotic activity of GHI, its ability to repair the cerebral microvessels and mitochondria, and the PI3K/AKT signaling pathway of GHI against cerebral ischemia. Western blot and immunohistochemical anal...

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Bibliografski detalji
Izdano u:Front Pharmacol
Glavni autori: Zhou, Huifen, He, Yu, Zhu, Jiaqi, Lin, Xiaojie, Chen, Juan, Shao, Chongyu, Wan, Haitong, Yang, Jiehong
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Pharmacology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8155598/
https://ncbi.nlm.nih.gov/pubmed/34054531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.650983
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