Guhong Injection Protects Against Apoptosis in Cerebral Ischemia by Maintaining Cerebral Microvasculature and Mitochondrial Integrity Through the PI3K/AKT Pathway

Guhong injection (GHI) can be used for the treatment of ischemic stroke. We investigated the antiapoptotic activity of GHI, its ability to repair the cerebral microvessels and mitochondria, and the PI3K/AKT signaling pathway of GHI against cerebral ischemia. Western blot and immunohistochemical anal...

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Publicado en:Front Pharmacol
Autores principales: Zhou, Huifen, He, Yu, Zhu, Jiaqi, Lin, Xiaojie, Chen, Juan, Shao, Chongyu, Wan, Haitong, Yang, Jiehong
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8155598/
https://ncbi.nlm.nih.gov/pubmed/34054531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.650983
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