Discovery of 5-Nitro-6-thiocyanatopyrimidines as Inhibitors of Cryptococcus neoformans and Cryptococcus gattii

[Image: see text] Opportunistic infections from pathogenic fungi present a major challenge to healthcare because of a very limited arsenal of antifungal drugs, an increasing population of immunosuppressed patients, and increased prevalence of resistant clinical strains due to overuse of the few avai...

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Bibliografiske detaljer
Udgivet i:ACS Med Chem Lett
Main Authors: Donlin, Maureen J., Lane, Thomas R., Riabova, Olga, Lepioshkin, Alexander, Xu, Evan, Lin, Jeffrey, Makarov, Vadim, Ekins, Sean
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2021
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8155264/
https://ncbi.nlm.nih.gov/pubmed/34055225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.1c00038
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