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Dual Targeting of Function–Structure for Effective Killing of Pathogenic Free-Living Amoebae

Here we discuss the potential value of targeting both the hardy structure of the cyst state of the parasite, in addition to the active trophozoite form, to provide target-directed inhibition as a viable drug strategy in the effective eradication of parasites.

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Bibliografiske detaljer
Udgivet i:ACS Med Chem Lett
Main Authors: Siddiqui, Ruqaiyyah, Abouleish, Mohamed Yehia, Khamis, Mustafa, Ibrahim, Taleb, Khan, Naveed Ahmed
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2021
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8155231/
https://ncbi.nlm.nih.gov/pubmed/34055204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.1c00200
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