Influence of NSAIDs and methotrexate on CD73 expression and glioma cell growth

Glioblastoma (GBM) is the most malignant and deadly brain tumor. GBM cells overexpress the CD73 enzyme, which controls the level of extracellular adenosine, an immunosuppressive molecule. Studies have shown that some nonsteroidal anti-inflammatory drugs (NSAIDs) and methotrexate (MTX) have antiproli...

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Bibliografski detalji
Izdano u:Purinergic Signal
Glavni autori: Lopes, Daniela Vasconcelos, de Fraga Dias, Amanda, Silva, Luiz Fernando Lopes, Scholl, Juliete Nathali, Sévigny, Jean, Battastini, Ana Maria Oliveira, Figueiró, Fabrício
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2021
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8155188/
https://ncbi.nlm.nih.gov/pubmed/33745072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-021-09775-w
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