Generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells

Compact cardiomyocytes that make up the ventricular wall of the adult heart represent an important therapeutic target population for modeling and treating cardiovascular diseases. Here, we established a differentiation strategy that promotes the specification, proliferation and maturation of compact...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Funakoshi, Shunsuke, Fernandes, Ian, Mastikhina, Olya, Wilkinson, Dan, Tran, Thinh, Dhahri, Wahiba, Mazine, Amine, Yang, Donghe, Burnett, Benjamin, Lee, Jeehoon, Protze, Stephanie, Bader, Gary D., Nunes, Sara S., Laflamme, Michael, Keller, Gordon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8155185/
https://ncbi.nlm.nih.gov/pubmed/34039977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23329-z
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