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Computational design of single-stranded DNA hairpin aptamers immobilized on a biosensor substrate
Aptamer interactions with a surface of attachment are central to the design and performance of aptamer-based biosensors. We have developed a computational modeling approach to study different system designs—including different aptamer-attachment ends, aptamer surface densities, aptamer orientations,...
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| Udgivet i: | Sci Rep |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8155018/ https://ncbi.nlm.nih.gov/pubmed/34040012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88796-2 |
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