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Computational design of single-stranded DNA hairpin aptamers immobilized on a biosensor substrate

Aptamer interactions with a surface of attachment are central to the design and performance of aptamer-based biosensors. We have developed a computational modeling approach to study different system designs—including different aptamer-attachment ends, aptamer surface densities, aptamer orientations,...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Jeddi, Iman, Saiz, Leonor
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8155018/
https://ncbi.nlm.nih.gov/pubmed/34040012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88796-2
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