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Phosphorylated Tau targeted Small-molecule PROTACs for the treatment of Alzheimer’s disease and Tauopathies
Tau is a microtubule-stabilizing protein that plays an important role in the formation of axonal microtubules in neurons. Phosphorylated tau (p-Tau) has received great attention in the field of Alzheimer’s disease (AD) as a potential therapeutic target due to its involvement with synaptic damage and...
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| Publicado en: | Biochim Biophys Acta Mol Basis Dis |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8154736/ https://ncbi.nlm.nih.gov/pubmed/33940164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2021.166162 |
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