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Computational Exploration of Ambiphilic Reactivity of Azides and Sustmann’s Paradigmatic Parabola

[Image: see text] We examine the theoretical underpinnings of the seminal discoveries by Reiner Sustmann about the ambiphilic nature of Huisgen’s phenyl azide cycloadditions. Density functional calculations with ωB97X-D and B2PLYP-D3 reproduce the experimental data and provide insights into ambiphil...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Chen, Pan-Pan, Ma, Pengchen, He, Xue, Svatunek, Dennis, Liu, Fang, Houk, Kendall N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8154615/
https://ncbi.nlm.nih.gov/pubmed/33769821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.1c00239
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