Fighting Shigella by Blocking Its Disease-Causing Toxin

[Image: see text] Shiga toxin is an AB(5) toxin produced by Shigella species, while related toxins are produced by Shiga toxin-producing Escherichia coli (STEC). Infection by Shigella can lead to bloody diarrhea followed by the often fatal hemolytic uremic syndrome (HUS). In the present paper, we ai...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Haksar, Diksha, Asadpoor, Mostafa, Heise, Torben, Shi, Jie, Braber, Saskia, Folkerts, Gert, Ballell, Lluis, Rodrigues, Janneth, Pieters, Roland J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8154557/
https://ncbi.nlm.nih.gov/pubmed/33909975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.1c00152
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