Engineering of Multiple Modules to Improve Amorphadiene Production in Bacillus subtilis Using CRISPR-Cas9

[Image: see text] Engineering strategies to improve terpenoids’ production in Bacillus subtilis mainly focus on 2C-methyl-d-erythritol-4-phosphate (MEP) pathway overexpression. To systematically engineer the chassis strain for higher amorphadiene (precursor of artemisinin) production, a clustered re...

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Pubblicato in:J Agric Food Chem
Autori principali: Song, Yafeng, He, Siqi, Abdallah, Ingy I., Jopkiewicz, Anita, Setroikromo, Rita, van Merkerk, Ronald, Tepper, Pieter G., Quax, Wim J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2021
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8154554/
https://ncbi.nlm.nih.gov/pubmed/33877851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jafc.1c00498
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