Human-derived Treg and MSC combination therapy may augment immunosuppressive potency in vitro, but did not improve blood brain barrier integrity in an experimental rat traumatic brain injury model

Traumatic brain injury (TBI) causes both physical disruption of the blood brain barrier (BBB) and altered immune responses that can lead to significant secondary brain injury and chronic inflammation within the central nervous system (CNS). Cell therapies, including mesenchymal stromal cells (MSC),...

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Pubblicato in:PLoS One
Autori principali: Caplan, Henry W., Prabhakara, Karthik S., Toledano Furman, Naama E., Zorofchian, Soheil, Martin, Cecilia, Xue, Hasen, Olson, Scott D., Cox, Charles S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8153465/
https://ncbi.nlm.nih.gov/pubmed/34038436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0251601
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