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Library construction of stereochemically diverse isomers of spirooliganin: their total synthesis and antiviral activity

The construction of libraries of stereoisomers of natural products serves as an important approach to investigating the correlation between the stereostructure and biological activity. However, the total synthesis and isomerzation of polycyclic scaffolds with multiple chrial centers are rare. Spiroo...

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Publicat a:Chem Sci
Autors principals: Wang, Ru-Bing, Ma, Shuang-Gang, Jamieson, Cooper S., Gao, Rong-Mei, Liu, Yun-Bao, Li, Yong, Wang, Xiao-Jing, Li, Yu-Huan, Houk, Kendall N., Qu, Jing, Yu, Shi-Shan
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society of Chemistry 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8153216/
https://ncbi.nlm.nih.gov/pubmed/34123328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1sc01277k
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