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Mesoporous Silica Nanoparticles Modified inside and out for ON:OFF pH-Modulated Cargo Release

Highly efficient pH-modulated cargo release was achieved with a new hybrid nanocarrier composed of a mesoporous silica core with functionalized pores and a grafted pH-responsive crosslinked polymer shell of 2-(diisopropylamino)ethyl methacrylate (pKa ≈ 6.5). The retention/release performance of the...

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Dettagli Bibliografici
Pubblicato in:Pharmaceutics
Autori principali: Gonçalves, José L. M., Lopes, Ana Beatriz C., Baleizão, Carlos, Farinha, José Paulo S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8153141/
https://ncbi.nlm.nih.gov/pubmed/34068257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13050716
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