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Inhibiting quinolone biosynthesis of Burkholderia
2-Alkylquinolones are important signalling molecules of Burkholderia species. We developed a substrate-based chemical probe against the central quinolone biosynthesis enzyme HmqD and applied it in competitive profiling experiments to discover the first known HmqD inhibitors. The most potent inhibito...
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| Publicado en: | Chem Sci |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Royal Society of Chemistry
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8153077/ https://ncbi.nlm.nih.gov/pubmed/34123319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc06167k |
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