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Predicting retrosynthetic pathways using transformer-based models and a hyper-graph exploration strategy

We present an extension of our Molecular Transformer model combined with a hyper-graph exploration strategy for automatic retrosynthesis route planning without human intervention. The single-step retrosynthetic model sets a new state of the art for predicting reactants as well as reagents, solvents...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Schwaller, Philippe, Petraglia, Riccardo, Zullo, Valerio, Nair, Vishnu H., Haeuselmann, Rico Andreas, Pisoni, Riccardo, Bekas, Costas, Iuliano, Anna, Laino, Teodoro
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152799/
https://ncbi.nlm.nih.gov/pubmed/34122839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc05704h
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