The ATM Gene in Breast Cancer: Its Relevance in Clinical Practice

Molecular alterations of the Ataxia-telangiectasia (AT) gene are frequently detected in breast cancer (BC), with an incidence ranging up to 40%. The mutated form, the Ataxia-telangiectasia mutated (ATM) gene, is involved in cell cycle control, apoptosis, oxidative stress, and telomere maintenance, a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Genes (Basel)
Hauptverfasser: Stucci, Luigia Stefania, Internò, Valeria, Tucci, Marco, Perrone, Martina, Mannavola, Francesco, Palmirotta, Raffaele, Porta, Camillo
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152746/
https://ncbi.nlm.nih.gov/pubmed/34068084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12050727
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