CAPS2 Deficiency Impairs the Release of the Social Peptide Oxytocin, as Well as Oxytocin-Associated Social Behavior

Ca(2+)-dependent activator protein for secretion 2 (CAPS2) regulates dense-core vesicle (DCV) exocytosis to facilitate peptidergic and catecholaminergic transmitter release. CAPS2 deficiency in mice has mild neuronal effects but markedly impairs social behavior. Rare de novo Caps2 alterations also o...

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Publicat a:J Neurosci
Autors principals: Fujima, Shuhei, Yamaga, Ryosuke, Minami, Haruka, Mizuno, Shota, Shinoda, Yo, Sadakata, Tetsushi, Abe, Manabu, Sakimura, Kenji, Sano, Yoshitake, Furuichi, Teiichi
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2021
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152601/
https://ncbi.nlm.nih.gov/pubmed/33846232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3240-20.2021
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