Ethyl cellulose coated sustained release aspirin spherules for treating COVID-19: DOE led rapid optimization using arbitrary interface; applicable for emergency situations

This work attempts to resolve one of the key issues related to the design and development of sustained-release spherule of aspirin for oral formulations, tailored to treat COVID-19. For that, in the Design of Experiments (DOE) an arbitrary interface, “coating efficiency” (CE) is introduced and scale...

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Vydáno v:Int J Biol Macromol
Hlavní autoři: Thrivikraman Nair, Sreejith, Kamalasanan, Kaladhar, Moidu, Ashna, Shyamsundar, Pooja, Nair, Lakshmi J., P, Venkatesan
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier B.V. 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152213/
https://ncbi.nlm.nih.gov/pubmed/34051259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijbiomac.2021.05.156
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