Beneficial and harmful effects of antidepressants versus placebo, ‘active placebo’, or no intervention for adults with major depressive disorder: a protocol for a systematic review of published and unpublished data with meta-analyses and trial sequential analyses

BACKGROUND: Major depressive disorder is one of the most common, burdensome, and costly psychiatric disorders worldwide. Antidepressants are frequently used to treat major depressive disorder. It has been shown repeatedly that antidepressants seem to reduce depressive symptoms with a statistically s...

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Vydáno v:Syst Rev
Hlavní autoři: Juul, Sophie, Siddiqui, Faiza, Barbateskovic, Marija, Jørgensen, Caroline Kamp, Hengartner, Michael Pascal, Kirsch, Irving, Gluud, Christian, Jakobsen, Janus Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
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Protocol
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152051/
https://ncbi.nlm.nih.gov/pubmed/34034811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13643-021-01705-6
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