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Thiazole–Chalcone Hybrids as Prospective Antitubercular and Antiproliferative Agents: Design, Synthesis, Biological, Molecular Docking Studies and In Silico ADME Evaluation

Compounds bearing thiazole and chalcone pharmacophores have been reported to possess excellent antitubercular and anticancer activities. In view of this, we designed, synthesized and characterized a novel series of thiazole–chalcone hybrids (1–20) and further evaluated them for antitubercular and an...

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Dettagli Bibliografici
Pubblicato in:Molecules
Autori principali: Kasetti, Ashok Babu, Singhvi, Indrajeet, Nagasuri, Ravindra, Bhandare, Richie R., Shaik, Afzal B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8151732/
https://ncbi.nlm.nih.gov/pubmed/34064806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26102847
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