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Leukotriene B(4) Receptors Are Necessary for the Stimulation of NLRP3 Inflammasome and IL-1β Synthesis in Neutrophil-Dominant Asthmatic Airway Inflammation

The stimulation of the NOD-, LRR- and pyrin domain-containing protein 3 (NLRP3) inflammasome and IL-1β synthesis are associated with chronic respiratory diseases such as neutrophil-dominant severe asthma. Leukotriene B(4) (LTB(4)) is a principal chemoattractant molecule for neutrophil recruitment, a...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Kwak, Dong-Wook, Park, Donghwan, Kim, Jae-Hong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8151312/
https://ncbi.nlm.nih.gov/pubmed/34064821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9050535
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