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Quality by Design Approach for the Development of Liposome Carrying Ghrelin for Intranasal Administration

The therapeutic use of peptides has increasingly recognized in the development of new therapies. However, the susceptible enzymatic cleavage is a barrier that needs to overcome. Nose-to-brain delivery associated with liposomes can protect peptides against biodegradation and improve the accessibility...

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Publicado en:Pharmaceutics
Autores principales: de Barros, Cecília, Aranha, Norberto, Severino, Patrícia, Souto, Eliana B., Zielińska, Aleksandra, Lopes, André, Rios, Alessandra, Batain, Fernando, Crescencio, Kessi, Chaud, Marco, Alves, Thais
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8151022/
https://ncbi.nlm.nih.gov/pubmed/34068793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13050686
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