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Ligand-induced structural changes analysis of ribose-binding protein as studied by molecular dynamics simulations

BACKGROUND: The ribose-binding protein (RBP) from Escherichia coli is one of the representative structures of periplasmic binding proteins. Binding of ribose at the cleft between two domains causes a conformational change corresponding to a closure of two domains around the ligand. The RBP has been...

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Detalhes bibliográficos
Publicado no:Technol Health Care
Main Authors: Li, Haiyan, Cao, Zanxia, Hu, Guodong, Zhao, Liling, Wang, Chunling, Wang, Jihua
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8150535/
https://ncbi.nlm.nih.gov/pubmed/33682750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/THC-218011
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