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Plasma Brain-Derived Neurotropic Factor Levels Are Associated with Aging and Smoking But Not with Future Dementia in the Rotterdam Study

BACKGROUND: Brain-derived neurotropic factor (BDNF) plays a vital role in neuronal survival and plasticity and facilitates long-term potentiation, essential for memory. Alterations in BDNF signaling have been associated with cognitive impairment, dementia, and Alzheimer’s disease. Although periphera...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Galle, Sara, Licher, Silvan, Milders, Maarten, Deijen, Jan Berend, Scherder, Erik, Drent, Madeleine, Ikram, Arfan, van Duijn, Cornelia M.
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8150496/
https://ncbi.nlm.nih.gov/pubmed/33646145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-200371
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