Nasal Extracts from Patients with Alzheimer’s Disease Induce Tau Aggregates in a Cellular Model of Tau Propagation

BACKGROUND: Emerging evidence indicates that the misfolded tau protein can propagate aggregates between cells in a prion-like manner. This prion activity has been typically studied in brain extracts of patients with Alzheimer’s disease (AD), but not in the olfactory region that can be a potential bi...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis Rep
Main Authors: Pahrudin Arrozi, Aslina, Yanagisawa, Daijiro, Kato, Tomoko, Akatsu, Hiroyasu, Hashizume, Yoshio, Kaneda, Daita, Tooyama, Ikuo
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2021
Assuntos:
Research Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8150252/
https://ncbi.nlm.nih.gov/pubmed/34113783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/ADR-210298
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