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Substrains matter in phenotyping of C57BL/6 mice

The inbred mouse strain C57BL/6 has been widely used as a background strain for spontaneous and induced mutations. Developed in the 1930s, the C57BL/6 strain diverged into two major groups in the 1950s, namely, C57BL/6J and C57BL/6N, and more than 20 substrains have been established from them worldw...

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Vydáno v:Exp Anim
Hlavní autoři: Mekada, Kazuyuki, Yoshiki, Atsushi
Médium: Artigo
Jazyk:Inglês
Vydáno: Japanese Association for Laboratory Animal Science 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8150240/
https://ncbi.nlm.nih.gov/pubmed/33441510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1538/expanim.20-0158
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