A Novel Cross-Linked Hemoglobin-Based Oxygen Carrier, YQ23, Extended the Golden Hour for Uncontrolled Hemorrhagic Shock in Rats and Miniature Pigs

Background: Hypotensive resuscitation is widely applied for trauma and war injury to reduce bleeding during damage-control resuscitation, but the treatment time window is limited in order to avoid hypoxia-associated organ injury. Whether a novel hemoglobin-based oxygen carrier (HBOC), YQ23 in this s...

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Publicat a:Front Pharmacol
Autors principals: Kuang, Lei, Zhu, Yu, Wu, Yue, Tian, Kunlun, Peng, Xiaoyong, Xue, Mingying, Xiang, Xinming, Lau, Billy, Tzang, Fei Chuen, Liu, Liangming, Li, Tao
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8149754/
https://ncbi.nlm.nih.gov/pubmed/34054533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.652716
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