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Generation of somatic mitochondrial DNA-replaced cells for mitochondrial dysfunction treatment

Mitochondrial diseases currently have no cure regardless of whether the cause is a nuclear or mitochondrial genome mutation. Mitochondrial dysfunction notably affects a wide range of disorders in aged individuals, including neurodegenerative diseases, cancers, and even senescence. Here, we present a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Maeda, Hideki, Kami, Daisuke, Maeda, Ryotaro, Shikuma, Akira, Gojo, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8149667/
https://ncbi.nlm.nih.gov/pubmed/34035362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90316-1
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