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Genetic influence of CYP2D6 on pharmacokinetics and acute subjective effects of LSD in a pooled analysis

Lysergic acid diethylamide (LSD) is a classic psychedelic substance that is used recreationally and investigated in psychiatric research. There are no pharmacogenetic studies on LSD. In vitro metabolic studies indicate that several cytochrome P450 (CYP) isoforms (e.g., CYP2D6, CYP1A2, and CYP2C9) ar...

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Detalhes bibliográficos
Publicado no:Sci Rep
Principais autores: Vizeli, Patrick, Straumann, Isabelle, Holze, Friederike, Schmid, Yasmin, Dolder, Patrick C., Liechti, Matthias E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8149637/
https://ncbi.nlm.nih.gov/pubmed/34035391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90343-y
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