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Integrative metabolomics and transcriptomics identifies itaconate as an adjunct therapy to treat ocular bacterial infection

The eye is highly susceptible to inflammation-mediated tissue damage evoked during bacterial infection. However, mechanisms regulating inflammation to protect the eye remain elusive. Here, we used integrated metabolomics and transcriptomics to show that the immunomodulatory metabolite itaconate and...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cell Rep Med
मुख्य लेखकों: Singh, Sukhvinder, Singh, Pawan Kumar, Jha, Alokkumar, Naik, Poonam, Joseph, Joveeta, Giri, Shailendra, Kumar, Ashok
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8149370/
https://ncbi.nlm.nih.gov/pubmed/34095879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2021.100277
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