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Oxidative stress and inflammation: determinants of anthracycline cardiotoxicity and possible therapeutic targets

Chemotherapy with anthracycline-based regimens remains a cornerstone of treatment of many solid and blood tumors but is associated with a significant risk of cardiotoxicity, which can manifest as asymptomatic left ventricular dysfunction or overt heart failure. These effects are typically dose-depen...

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Bibliographische Detailangaben
Veröffentlicht in:Heart Fail Rev
Hauptverfasser: Fabiani, Iacopo, Aimo, Alberto, Grigoratos, Chrysanthos, Castiglione, Vincenzo, Gentile, Francesco, Saccaro, Luigi F, Arzilli, Chiara, Cardinale, Daniela, Passino, Claudio, Emdin, Michele
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8149360/
https://ncbi.nlm.nih.gov/pubmed/33319255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10741-020-10063-9
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