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Entrectinib: A Review in NTRK+ Solid Tumours and ROS1+ NSCLC

Entrectinib (Rozlytrek(®)) is an orally active, CNS-penetrant, small-molecule, selective inhibitor of the tropomyosin receptor tyrosine kinases TRKA/B/C [encoded by the neurotrophic tyrosine receptor kinase (NTRK) genes NTRK1/2/3, respectively], the proto-oncogene tyrosine-protein kinase ROS1 (ROS1)...

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Dades bibliogràfiques
Publicat a:Drugs
Autor principal: Frampton, James E.
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8149347/
https://ncbi.nlm.nih.gov/pubmed/33871816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40265-021-01503-3
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