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Entrectinib: A Review in NTRK+ Solid Tumours and ROS1+ NSCLC
Entrectinib (Rozlytrek(®)) is an orally active, CNS-penetrant, small-molecule, selective inhibitor of the tropomyosin receptor tyrosine kinases TRKA/B/C [encoded by the neurotrophic tyrosine receptor kinase (NTRK) genes NTRK1/2/3, respectively], the proto-oncogene tyrosine-protein kinase ROS1 (ROS1)...
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| Publicado no: | Drugs |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8149347/ https://ncbi.nlm.nih.gov/pubmed/33871816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40265-021-01503-3 |
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