Internal modulation of proteolysis in vascular extracellular matrix remodeling: role of ADAM metallopeptidase with thrombospondin type 1 motif 5 in the development of intracranial aneurysm rupture

Intracranial aneurysms (IAs) are common cerebrovascular diseases that carry a high mortality rate, and the mechanisms that contribute to IA formation and rupture have not been elucidated. ADAMTS-5 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif 5) is a secreted proteinase involved in matrix...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Wang, Weihan, Zhang, Hao, Hou, Changkai, Liu, Quanlei, Yang, Shuyuan, Zhang, Zhen, Yang, Weidong, Yang, Xinyu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8148490/
https://ncbi.nlm.nih.gov/pubmed/33934089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202948
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