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The human papillomavirus oncoproteins: a review of the host pathways targeted on the road to transformation

Persistent infection with high-risk human papillomaviruses (HR-HPVs) is the causal factor in over 99 % of cervical cancer cases, and a significant proportion of oropharyngeal and anogenital cancers. The key drivers of HPV-mediated transformation are the oncoproteins E5, E6 and E7. Together, they act...

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Bibliografiske detaljer
Udgivet i:J Gen Virol
Main Authors: Scarth, James A., Patterson, Molly R., Morgan, Ethan L., Macdonald, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: Microbiology Society 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8148304/
https://ncbi.nlm.nih.gov/pubmed/33427604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.001540
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