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Functional characterization of N-octyl 4-methylamphetamine variants and related bivalent compounds at the dopamine and serotonin transporters using Ca(2+) channels as sensors

The early characterization of ligands at the dopamine and serotonin transporters, DAT and SERT, respectively, is important for drug discovery, forensic sciences, and drug abuse research. 4-Methyl amphetamine (4-MA) is a good example of an abused drug whose overdose can be fatal. It is a potent subst...

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Detalhes bibliográficos
Publicado no:Toxicol Appl Pharmacol
Main Authors: Ruchala, Iwona, Battisti, Umberto M., Nguyen, Vy T., Chen, Rita Yu-Tzu, Glennon, Richard A., Eltit, Jose M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8148225/
https://ncbi.nlm.nih.gov/pubmed/33785354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2021.115513
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