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Gut microbiota mediates the absorption of FLZ, a new drug for Parkinson's disease treatment
The gut microbiota plays an important role in regulating the pharmacokinetics and pharmacodynamics of many drugs. FLZ, a novel squamosamide derivative, has been shown to have neuroprotective effects on experimental Parkinson's disease (PD) models. FLZ is under phase Ⅰ clinical trial now, while...
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| Publicado no: | Acta Pharm Sin B |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8148066/ https://ncbi.nlm.nih.gov/pubmed/34094829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2021.01.009 |
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