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Regio- and diastereoselective dearomatizations of N-alkyl activated azaarenes: the maximization of the reactive sites

An unprecedented base-promoted multi-component one-pot dearomatization of N-alkyl activated azaarenes was developed, which enabled the synthesis of complex and diverse bridged cyclic polycycles with multiple stereocenters in a highly regio- and diastereoselective manner. Besides, we realized the ste...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Miao, Hong-Jie, Wang, Le-Le, Han, Hua-Bin, Zhao, Yong-De, Wang, Qi-Lin, Bu, Zhan-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147894/
https://ncbi.nlm.nih.gov/pubmed/34123266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc04880d
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